Migren, d\u00fcnya genelinde yakla\u015f\u0131k yedi ki\u015fiden birini etkiliyor ve kad\u0131nlarda daha s\u0131k g\u00f6r\u00fcl\u00fcyor. Genellikle bulant\u0131 e\u015fli\u011finde ve \u0131\u015f\u0131\u011fa veya sese kar\u015f\u0131 artan hassasiyetle birlikte gelen \u015fiddetli ba\u015f a\u011fr\u0131lar\u0131 n\u00f6betleri, ya\u015fam kalitesini \u00f6nemli \u00f6l\u00e7\u00fcde d\u00fc\u015f\u00fcr\u00fcyor. Klasik ila\u00e7 tedavilerinin s\u0131n\u0131rlar\u0131, \u00f6nemli yan etkilere neden olabilmeleri veya tolere edilememeleri nedeniyle, ila\u00e7 d\u0131\u015f\u0131 yakla\u015f\u0131mlar giderek daha fazla ilgi g\u00f6r\u00fcyor.<\/p>\n
Magnezyum, sinir sisteminin d\u00fczg\u00fcn \u00e7al\u0131\u015fmas\u0131 i\u00e7in temel bir mineral olup, n\u00f6ronal aktivitenin d\u00fczenlenmesinde kilit bir rol oynar. \u00d6zellikle NMDA resept\u00f6rlerini bloke ederek, a\u011fr\u0131 iletiminde ve yayg\u0131n kortikal depresyon fenomeninde rol oynar; bu s\u00fcre\u00e7 aura ile birlikte migrenle ili\u015fkilidir. Magnezyum eksikli\u011fi, n\u00f6ronlar\u0131n uyar\u0131labilirli\u011fini art\u0131rarak n\u00f6betlerin ortaya \u00e7\u0131kmas\u0131n\u0131 kolayla\u015ft\u0131rabilir.<\/p>\n
Bir\u00e7ok klinik deneme, migrenin \u00f6nlenmesinde oral magnezyumun etkinli\u011fini de\u011ferlendirdi. Sonu\u00e7lar, magnezyum sitrat veya oksit gibi belirli magnezyum formlar\u0131n\u0131n, g\u00fcnl\u00fck 500 ila 600 mg dozlarda, n\u00f6betlerin s\u0131kl\u0131\u011f\u0131n\u0131 ve \u015fiddetini \u00f6nemli \u00f6l\u00e7\u00fcde azaltt\u0131\u011f\u0131n\u0131 g\u00f6steriyor. \u00d6rne\u011fin, bir \u00e7al\u0131\u015fma magnezyum sitrat takviyesinin, ayl\u0131k migren say\u0131s\u0131n\u0131 plaseboya k\u0131yasla daha belirgin \u015fekilde azaltt\u0131\u011f\u0131n\u0131 ortaya koydu. Ba\u015fka bir ara\u015ft\u0131rma ise magnezyum oksitin, yayg\u0131n olarak re\u00e7ete edilen sodyum valproat kadar etkili oldu\u011funu, ancak daha az ciddi yan etkiye sahip oldu\u011funu do\u011frulad\u0131.<\/p>\n
Ancak, t\u00fcm magnezyum t\u00fcrleri e\u015fit de\u011fildir. Magnezyum aspartat gibi baz\u0131 form\u00fclasyonlar\u0131n pl<\/p>\n
DOI\u00a0:<\/strong> https:\/\/doi.org\/10.1186\/s41983-026-01150-z<\/a><\/p>\n Titre\u00a0:<\/strong> Efficacy of magnesium supplementation in the prophylaxis of migraine: a systematic review of clinical trials comparing oral magnesium to placebo or standard care<\/p>\n Revue : <\/strong> The Egyptian Journal of Neurology, Psychiatry and Neurosurgery<\/p>\n \u00c9diteur : <\/strong> Springer Science and Business Media LLC<\/p>\n Auteurs : <\/strong> Habiblah Jagunmolu; Emmanuel Oyetola; Yusuff Lawal; Samuel Oyelude; Oluwatomisin Ogunsola; Abdulmujeeb Oladeji; Salahudeen Ogundipe; Mukhtar Ibrahim; Dhikrat Ajibade; Oluwadamilola Ariyo; Kamil Ajagbe<\/p>\n","protected":false},"excerpt":{"rendered":" Magnezyum migreni etkili bir \u015fekilde azaltabilir mi? Migren, d\u00fcnya genelinde yakla\u015f\u0131k yedi ki\u015fiden birini etkiliyor ve kad\u0131nlarda daha s\u0131k g\u00f6r\u00fcl\u00fcyor. Genellikle bulant\u0131 e\u015fli\u011finde ve \u0131\u015f\u0131\u011fa veya sese kar\u015f\u0131 artan hassasiyetle birlikte gelen \u015fiddetli ba\u015f a\u011fr\u0131lar\u0131 n\u00f6betleri, ya\u015fam kalitesini \u00f6nemli \u00f6l\u00e7\u00fcde d\u00fc\u015f\u00fcr\u00fcyor. Klasik ila\u00e7 tedavilerinin s\u0131n\u0131rlar\u0131, \u00f6nemli yan etkilere neden olabilmeleri veya tolere edilememeleri nedeniyle, ila\u00e7… Okumaya devam et Magnezyum migreni etkili bir \u015fekilde azaltabilir mi?<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-23","post","type-post","status-publish","format-standard","hentry","category-uluslararasi","entry"],"_links":{"self":[{"href":"https:\/\/internationalsciencereview.com\/tr\/wp-json\/wp\/v2\/posts\/23","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/internationalsciencereview.com\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/internationalsciencereview.com\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/internationalsciencereview.com\/tr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/internationalsciencereview.com\/tr\/wp-json\/wp\/v2\/comments?post=23"}],"version-history":[{"count":1,"href":"https:\/\/internationalsciencereview.com\/tr\/wp-json\/wp\/v2\/posts\/23\/revisions"}],"predecessor-version":[{"id":24,"href":"https:\/\/internationalsciencereview.com\/tr\/wp-json\/wp\/v2\/posts\/23\/revisions\/24"}],"wp:attachment":[{"href":"https:\/\/internationalsciencereview.com\/tr\/wp-json\/wp\/v2\/media?parent=23"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/internationalsciencereview.com\/tr\/wp-json\/wp\/v2\/categories?post=23"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/internationalsciencereview.com\/tr\/wp-json\/wp\/v2\/tags?post=23"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}